The role of thioredoxin reductases in brain development.

The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin reductases in brain using mice with nervous system (NS)-specific deletion of cytosolic (Txnrd1) and mitocho...

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Bibliographic Details
Main Authors: Jonna Soerensen, Cemile Jakupoglu, Heike Beck, Heidi Förster, Jörg Schmidt, Wolfgang Schmahl, Ulrich Schweizer, Marcus Conrad, Markus Brielmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2263137?pdf=render