Origin of serpin-mediated regulation of coagulation and blood pressure.

Origin of serpin-mediated regulation of coagulation and blood pressure.

Vertebrates evolved an endothelium-lined hemostatic system and a pump-driven pressurized circulation with a finely-balanced coagulation cascade and elaborate blood pressure control over the past 500 million years. Genome analyses have identified principal components of the ancestral coagulation syst...

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Bibliographic Details
Main Authors: Yunjie Wang, Katharina Köster, Martina Lummer, Hermann Ragg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4026541?pdf=render

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