Toll-like receptor 4 and protease-activated receptor 2 in physiology and pathophysiology of the nervous system: more than just receptor cooperation?

Toll-like receptor 4 and protease-activated receptor 2 in physiology and pathophysiology of the nervous system: more than just receptor cooperation?

Toll-like receptor 4 (TLR4) and protease-activated receptor 2 (PAR2) play pivotal roles in the mammalian innate immune response. Notably, in addition to their involvement in detection of invading pathogens, PAR2 and TLR4 modulate the levels of cell death-induced sterile inflammation by activating pr...

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Bibliographic Details
Main Authors: Darius Widera, Rocío Martínez Aguilar, Graeme S Cottrell
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
signaling; inflammation; proteases; myeloid of differentiation primary response gene 88; TIR-domain containing adaptor inducing interferon; lipopolysaccharide; TLR4; PAR2
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1196;epage=1201;aulast=Widera

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1196;epage=1201;aulast=Widera

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