Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels

Thymoquinone attenuates rheumatoid arthritis by downregulating TLR2, TLR4, TNF-α, IL-1, and NFκB expression levels

Background: Thymoquinone (TQ), the most important active principle of Nigella sativa is known to have anti-inflammatory, analgesic, antimicrobial and antioxidant properties. Aim: The present study was designed to see the anti-arthritic effect of TQ in rat model of arthritis. Methods: In the current...

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Bibliographic Details
Main Authors:	Sabeen Arjumand, Muhammad Shahzad, Arham Shabbir, Muhammad Zubair Yousaf
Format:	Article
Language:	English
Published:	Elsevier 2019-03-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Rheumatoid arthritis Thymoquinone FCA Toll like receptors NFκB
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332218370926

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