Hypermethylation-Associated Silencing of miR-125a and miR-125b: A Potential Marker in Colorectal Cancer

Background. MicroRNAs (miRNAs) have been found to be downregulated in human colorectal cancer (CRC), and some of them may function as tumor suppressor genes (TSGs). Aberrant methylation triggers the inactivation of TSGs during tumorigenesis. Patients and Methods. We investigated the methylation stat...

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Bibliographic Details
Main Authors: Hui Chen, Zhiying Xu
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2015/345080