A powerful microbial group association test based on the higher criticism analysis for sparse microbial association signals
Abstract Background In human microbiome studies, it is crucial to evaluate the association between microbial group (e.g., community or clade) composition and a host phenotype of interest. In response, a number of microbial group association tests have been proposed, which account for the unique feat...
Main Authors: | Hyunwook Koh, Ni Zhao |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | Microbiome |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40168-020-00834-9 |
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