Early Use of the NMDA Receptor Antagonist Ketamine in Refractory and Superrefractory Status Epilepticus

Refractory status epilepticus (RSE) and superrefractory status epilepticus (SRSE) pose a difficult clinical challenge. Multiple cerebral receptor and transporter changes occur with prolonged status epilepticus leading to pharmacoresistance patterns unfavorable for conventional antiepileptics. In par...

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Bibliographic Details
Main Author: F. A. Zeiler
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2015/831260