Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

Stratification of ovarian tumor pathology by expression of programmed cell death-1 (PD-1) and PD-ligand- 1 (PD-L1) in ovarian cancer

Abstract Background Ovarian cancer is the major cause of death among gynecologic cancers with 75% of patients diagnosed with advanced disease, and only 20% of these patients having a survival duration of five years. Treatments blocking immune checkpoint molecules, programmed cell death (PD-1) or its...

Full description

Bibliographic Details
Main Authors: Maureen L. Drakes, Swati Mehrotra, Monica Aldulescu, Ronald K. Potkul, Yueying Liu, Anne Grisoli, Cara Joyce, Timothy E. O’Brien, M. Sharon Stack, Patrick J. Stiff
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Ovarian Research
Subjects:
Programmed cell death-1
Programmed cell death-1 ligand
High grade disease
Cancer immunotherapy
Ovarian cancer
Online Access:http://link.springer.com/article/10.1186/s13048-018-0414-z

Internet

http://link.springer.com/article/10.1186/s13048-018-0414-z

Similar Items