Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.

Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.

MTAP is a ubiquitously expressed gene important for adenine and methionine salvage. The gene is located at 9p21, a chromosome region often deleted in breast carcinomas, similar to CDKN2A, a recognized tumor suppressor gene. Several research groups have shown that MTAP acts as a tumor suppressor, and...

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Bibliographic Details
Main Authors: Sarah Franco Vieira de Oliveira, Monica Ganzinelli, Rosaria Chilà, Leandro Serino, Marcos Euzébio Maciel, Cícero de Andrade Urban, Rubens Silveira de Lima, Iglenir João Cavalli, Daniele Generali, Massimo Broggini, Giovanna Damia, Enilze Maria de Souza Fonseca Ribeiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709099?pdf=render

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http://europepmc.org/articles/PMC4709099?pdf=render

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