Mapping Challenging Mutations by Whole-Genome Sequencing

Whole-genome sequencing provides a rapid and powerful method for identifying mutations on a global scale, and has spurred a renewed enthusiasm for classical genetic screens in model organisms. The most commonly characterized category of mutation consists of monogenic, recessive traits, due to their...

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Bibliographic Details
Main Authors: Harold E. Smith, Amy S. Fabritius, Aimee Jaramillo-Lambert, Andy Golden
Format: Article
Language:English
Published: Oxford University Press 2016-05-01
Series:G3: Genes, Genomes, Genetics
Subjects:
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.028316