Calibrating models of cancer invasion: parameter estimation using approximate Bayesian computation and gradient matching

We present two different methods to estimate parameters within a partial differential equation model of cancer invasion. The model describes the spatio-temporal evolution of three variables—tumour cell density, extracellular matrix density and matrix degrading enzyme concentration—in a one-dimension...

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Bibliographic Details
Main Authors: Yunchen Xiao, Len Thomas, Mark A. J. Chaplain
Format: Article
Language:English
Published: The Royal Society 2021-06-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.202237