ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS)
The anticoagulant effect of salivary secretion of ticks Argas persicus was studied. The experiments were conducted on aorta preparations isolated from the chest of white outbread rats. Isometric contraction in an isolated muscle preparation was registered by mechanotron. To determine the anticoagula...
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Federal Scientific Centre VIEV
2016-05-01
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| Series: | Российский паразитологический журнал |
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| Online Access: | https://vniigis.elpub.ru/jour/article/view/222 |
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doaj-4138266f84b64cba90cbbb7e6821f6dd2021-09-16T19:27:09ZrusFederal Scientific Centre VIEVРоссийский паразитологический журнал1998-84352541-78432016-05-013512429222ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS)A. U. Mirzayeva0F. D. Akramova1S. Sh. Hushmatov2The Institute of Gene Pool of Plants and Animals world of Uzbekistan Academy of Sciences, 100053 Uzbekistan, Tashkent, 232 Bogishamol st.The Institute of Gene Pool of Plants and Animals world of Uzbekistan Academy of Sciences, 100053 Uzbekistan, Tashkent, 232 Bogishamol st.Scientific Institute of Bioorganic Chemistry named after A.S. Sadykov, Academy of Sciences of Republic Uzbekistan, 100170 Tashkent, 83. Mirzo Ulugbek st.The anticoagulant effect of salivary secretion of ticks Argas persicus was studied. The experiments were conducted on aorta preparations isolated from the chest of white outbread rats. Isometric contraction in an isolated muscle preparation was registered by mechanotron. To determine the anticoagulant mechanism of blood plasma at deficiency of factors X, XI, IX and VIII we used the activated partial thromboplastin time. It was determined that the process of blood coagulation in rats slows down. The coagulation values depend on the concentration of tested secretions. It was found that at concentration 150 mkg /ml, the blood coagulation rate fell to 78,4 %. The role of calcium ions in regulation of vascular smooth muscle cells (VSMCs) contraction was determined. The components of salivary glands A. Persicus have a relaxation effect on the contraction of rat aortic ring preparationhttps://vniigis.elpub.ru/jour/article/view/222ticksargas persicussalivary glandsanticoagulantblood systembiologically active compounds |
| collection |
DOAJ |
| language |
Russian |
| format |
Article |
| sources |
DOAJ |
| author |
A. U. Mirzayeva F. D. Akramova S. Sh. Hushmatov |
| spellingShingle |
A. U. Mirzayeva F. D. Akramova S. Sh. Hushmatov ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) Российский паразитологический журнал ticks argas persicus salivary glands anticoagulant blood system biologically active compounds |
| author_facet |
A. U. Mirzayeva F. D. Akramova S. Sh. Hushmatov |
| author_sort |
A. U. Mirzayeva |
| title |
ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) |
| title_short |
ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) |
| title_full |
ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) |
| title_fullStr |
ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) |
| title_full_unstemmed |
ON PHYSIOLOGICAL MECHANISM OF SALIVARY SECRETION IN TICKS ARGAS PERSICUS OKEN, 1818 (ARGASIDAE, ARGAS) |
| title_sort |
on physiological mechanism of salivary secretion in ticks argas persicus oken, 1818 (argasidae, argas) |
| publisher |
Federal Scientific Centre VIEV |
| series |
Российский паразитологический журнал |
| issn |
1998-8435 2541-7843 |
| publishDate |
2016-05-01 |
| description |
The anticoagulant effect of salivary secretion of ticks Argas persicus was studied. The experiments were conducted on aorta preparations isolated from the chest of white outbread rats. Isometric contraction in an isolated muscle preparation was registered by mechanotron. To determine the anticoagulant mechanism of blood plasma at deficiency of factors X, XI, IX and VIII we used the activated partial thromboplastin time. It was determined that the process of blood coagulation in rats slows down. The coagulation values depend on the concentration of tested secretions. It was found that at concentration 150 mkg /ml, the blood coagulation rate fell to 78,4 %. The role of calcium ions in regulation of vascular smooth muscle cells (VSMCs) contraction was determined. The components of salivary glands A. Persicus have a relaxation effect on the contraction of rat aortic ring preparation |
| topic |
ticks argas persicus salivary glands anticoagulant blood system biologically active compounds |
| url |
https://vniigis.elpub.ru/jour/article/view/222 |
| work_keys_str_mv |
AT aumirzayeva onphysiologicalmechanismofsalivarysecretioninticksargaspersicusoken1818argasidaeargas AT fdakramova onphysiologicalmechanismofsalivarysecretioninticksargaspersicusoken1818argasidaeargas AT sshhushmatov onphysiologicalmechanismofsalivarysecretioninticksargaspersicusoken1818argasidaeargas |
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