A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I
Glycosylation, a common modification of cellular proteins and lipids, is often altered in diseases and pathophysiological states such as hypoxia, yet the underlying molecular causes remain poorly understood. By utilizing lectin microarray glycan profiling, Golgi pH and redox screens, we show here th...
Main Authors: | Antti Hassinen, Fawzi Khoder-Agha, Elham Khosrowabadi, Daniela Mennerich, Deborah Harrus, Maxence Noel, Elitsa Y. Dimova, Tuomo Glumoff, Anne Harduin-Lepers, Thomas Kietzmann, Sakari Kellokumpu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-06-01
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Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231719301983 |
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