Trastuzumab-Modified Gold Nanoparticles Labeled with <sup>211</sup>At as a Prospective Tool for Local Treatment of HER2-Positive Breast Cancer

Trastuzumab-Modified Gold Nanoparticles Labeled with <sup>211</sup>At as a Prospective Tool for Local Treatment of HER2-Positive Breast Cancer

Highly localized radiotherapy with radionuclides is a commonly used treatment modality for patients with unresectable solid tumors. Herein, we propose a novel &#945;-nanobrachytherapy approach for selective therapy of human epidermal growth factor receptor 2 (HER2)-positive breast cancer. This u...

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Bibliographic Details
Main Authors: Łucja Dziawer, Agnieszka Majkowska-Pilip, Damian Gaweł, Marlena Godlewska, Marek Pruszyński, Jerzy Jastrzębski, Bogdan Wąs, Aleksander Bilewicz
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Nanomaterials
Subjects:
α-nanobrachytherapy
monoclonal antibody
SKOV-3 ovarian cell line
HER2 receptor
α-emitter <sup>211</sup>At
Online Access:https://www.mdpi.com/2079-4991/9/4/632

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