Co-Amorphous Formulations of Furosemide with Arginine and P-Glycoprotein Inhibitor Drugs

Co-Amorphous Formulations of Furosemide with Arginine and P-Glycoprotein Inhibitor Drugs

In this study, the amino acid arginine (ARG) and P-glycoprotein (P-gp) inhibitors verapamil hydrochloride (VER), piperine (PIP) and quercetin (QRT) were used as co-formers for co-amorphous mixtures of a Biopharmaceutics classification system (BCS) class IV drug, furosemide (FUR). FUR mixtures with V...

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Bibliographic Details
Main Authors: Marika Ruponen, Konsta Kettunen, Monica Santiago Pires, Riikka Laitinen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
co-amorphous
dissolution
solubility
stability
permeation
P-gp inhibitor
Online Access:https://www.mdpi.com/1999-4923/13/2/171

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https://www.mdpi.com/1999-4923/13/2/171

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