Mendelian randomization analysis identified genes pleiotropically associated with central corneal thickness

Abstract Objective To prioritize genes that were pleiotropically or potentially causally associated with central corneal thickness (CCT). Methods We applied the summary data-based Mendelian randomization (SMR) method integrating summarized data of genome-wide association study (GWAS) on CCT and expr...

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Bibliographic Details
Main Authors: Zhikun Yang, Jingyun Yang, Di Liu, Weihong Yu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-07860-3