Clinical application of gonadotropin-releasing hormone analogs in children and adolescents

Clinical application of gonadotropin-releasing hormone analogs in children and adolescents

Although the increasing incidence of central precocious puberty (CPP) in Korea has recently raised public concerns about health and growth problems, there are many areas of uncertainty regarding the pathogenesis, diagnosis, and management of CPP. In this paper, we review the definition of precocity,...

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Main Author: Ho-Seong Kim
Format: Article
Language:English
Published: Korean Pediatric Society 2010-03-01
Series:Korean Journal of Pediatrics
Online Access:http://www.kjp.or.kr/upload/2010530303-20100419142019.PDF
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spelling doaj-4101119819954513aee2af19b077bdea2020-11-24T23:14:18ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582010-03-0153329429910.3345/kjp.2010.53.3.294Clinical application of gonadotropin-releasing hormone analogs in children and adolescentsHo-Seong KimAlthough the increasing incidence of central precocious puberty (CPP) in Korea has recently raised public concerns about health and growth problems, there are many areas of uncertainty regarding the pathogenesis, diagnosis, and management of CPP. In this paper, we review the definition of precocity, the assessment of CPP, and the hormonal abnormalities that support the diagnosis. In addition, we review the practical guidelines regarding the clinical use of gonadotropin-releasing hormone analogs in children with CPP. Indications for treatment, determination of dosage, monitoring during treatment, and discontinuation of therapy are discussed.http://www.kjp.or.kr/upload/2010530303-20100419142019.PDF
collection DOAJ
language English
format Article
sources DOAJ
author Ho-Seong Kim
spellingShingle Ho-Seong Kim
Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
Korean Journal of Pediatrics
author_facet Ho-Seong Kim
author_sort Ho-Seong Kim
title Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
title_short Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
title_full Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
title_fullStr Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
title_full_unstemmed Clinical application of gonadotropin-releasing hormone analogs in children and adolescents
title_sort clinical application of gonadotropin-releasing hormone analogs in children and adolescents
publisher Korean Pediatric Society
series Korean Journal of Pediatrics
issn 1738-1061
2092-7258
publishDate 2010-03-01
description Although the increasing incidence of central precocious puberty (CPP) in Korea has recently raised public concerns about health and growth problems, there are many areas of uncertainty regarding the pathogenesis, diagnosis, and management of CPP. In this paper, we review the definition of precocity, the assessment of CPP, and the hormonal abnormalities that support the diagnosis. In addition, we review the practical guidelines regarding the clinical use of gonadotropin-releasing hormone analogs in children with CPP. Indications for treatment, determination of dosage, monitoring during treatment, and discontinuation of therapy are discussed.
url http://www.kjp.or.kr/upload/2010530303-20100419142019.PDF
work_keys_str_mv AT hoseongkim clinicalapplicationofgonadotropinreleasinghormoneanalogsinchildrenandadolescents
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