IFN-Lambda 3 Mediates Antiviral Protection Against Porcine Epidemic Diarrhea Virus by Inducing a Distinct Antiviral Transcript Profile in Porcine Intestinal Epithelia

IFN-Lambda 3 Mediates Antiviral Protection Against Porcine Epidemic Diarrhea Virus by Inducing a Distinct Antiviral Transcript Profile in Porcine Intestinal Epithelia

Type III interferon-lambda (IFN-λ) plays a critical role against infection, particularly in mucosal infection in the respiratory and gastrointestinal tract. Our study and other previous studies have shown that porcine IFN-λ more efficiently curtails the infection of porcine epidemic diarrhea virus (...

Full description

Bibliographic Details
Main Authors: Liang Li, Mei Xue, Fang Fu, Lingdan Yin, Li Feng, Pinghuang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
interferon-lambda 3
interferon alpha
RNA-seq
enteroids
PEDV
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02394/full

Similar Items

Similar Items