Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs
<p>Abstract</p> <p>Background</p> <p>The etiology of schizophrenia is unknown, but neurodevelopmental disturbances, myelin- and oligodendrocyte abnormalities and synaptic dysfunction have been suggested as pathophysiological factors in this severe psychiatric disorder....
Main Authors: | Vik-Mo Audun O, Skrede Silje, Fernø Johan, Håvik Bjarte, Steen Vidar M |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2006-10-01
|
Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/7/69 |
Similar Items
-
Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition?1
by: Silje Skrede, et al.
Published: (2013-02-01) -
Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment.
by: Silje Skrede, et al.
Published: (2012-01-01) -
SREBP-1-independent regulation of lipogenic gene expression in adipocytes
by: Motohiro Sekiya, et al.
Published: (2007-07-01) -
ADD-1/SREBP-1 is a major determinant of tissue differential lipogenic capacity in mammalian and avian species
by: Florence Gondret, et al.
Published: (2001-01-01) -
Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs
by: Takashi Matsuzaka, et al.
Published: (2002-06-01)