Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF-β Signal Pathway

We investigated the effect of Dalbergioidin (DAL), a well-known natural product extracted from Uraria crinita, on doxorubicin- (DXR-) induced renal fibrosis in mice. The mice were pretreated for 7 days with DAL followed by a single injection of DXR (10 mg/kg) via the tail vein. Renal function was an...

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Bibliographic Details
Main Authors: Xianguo Ren, Yun Bo, Junting Fan, Maosheng Chen, Daliang Xu, Yang Dong, Haowei He, Xianzhi Ren, Rong Qu, Yulian Jin, Weihong Zhao, Changliang Xu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/5147571