Dual mechanisms of translation initiation of the full-length HIV-1 mRNA contribute to gag synthesis.

Dual mechanisms of translation initiation of the full-length HIV-1 mRNA contribute to gag synthesis.

The precursor group-specific antigen (pr55(Gag)) is central to HIV-1 assembly. Its expression alone is sufficient to assemble into virus-like particles. It also selects the genomic RNA for encapsidation and is involved in several important virus-host interactions for viral assembly and restriction,...

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Bibliographic Details
Main Authors: Anne Monette, Fernando Valiente-Echeverría, Matias Rivero, Éric A Cohen, Marcelo Lopez-Lastra, Andrew J Mouland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3702555?pdf=render

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