Circulating Total Cell-Free DNA Levels Are Increased in Hypertensive Disorders of Pregnancy and Associated with Prohypertensive Factors and Adverse Clinical Outcomes

Circulating Total Cell-Free DNA Levels Are Increased in Hypertensive Disorders of Pregnancy and Associated with Prohypertensive Factors and Adverse Clinical Outcomes

Previous studies have described increased circulating cell-free DNA (cfDNA) in hypertensive disorders of pregnancy (HDP). Here, we aimed first to confirm this information using a simple, but sensible fluorescent assay, and second to investigate whether total cfDNA is associated with circulating fact...

Full description

Bibliographic Details
Main Authors: Lorena M. Amaral, Valeria C. Sandrim, Matthew E. Kutcher, Frank T. Spradley, Ricardo C. Cavalli, Jose E. Tanus-Santos, Ana C. Palei
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
adverse maternal-fetal outcomes
biomarkers
cell-free DNA
gestational hypertension
preeclampsia
Online Access:https://www.mdpi.com/1422-0067/22/2/564

Internet

https://www.mdpi.com/1422-0067/22/2/564

Similar Items