The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy.

The KCa3.1 blocker TRAM34 reverses renal damage in a mouse model of established diabetic nephropathy.

Despite optimal control of hyperglycaemia, hypertension, and dyslipidaemia, the number of patients with diabetic nephropathy (DN) continues to grow. Strategies to target various signaling pathways to prevent DN have been intensively investigated in animal models and many have been proved to be promi...

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Bibliographic Details
Main Authors:	Chunling Huang, Ling Zhang, Ying Shi, Hao Yi, Yongli Zhao, Jason Chen, Carol A Pollock, Xin-Ming Chen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC5806905?pdf=render

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