Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome

Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome

Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver...

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Main Authors: Xiaopeng Yang, Sanming Chai, Xining Xu, Ling Hui, Meiliang Wang
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-12-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
acute kidney injury
liver involvement
thrombocytopenia
Online Access:https://jcdr.net/articles/PDF/10987/29306-CE(RA1)_F(GG)_PF1(PB_AP)_PFA(MJ_GG)_PF2(EK_MJ_AP).pdf
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spelling doaj-40dccd0591b7475a95c045e808bf9de02020-11-25T03:07:28ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-12-011112IR01IR0310.7860/JCDR/2017/29306.10987Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal SyndromeXiaopeng Yang0Sanming Chai1Xining Xu2Ling Hui3Meiliang Wang4Intermediate Physician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.Senior Resident, Reproductive Medicine Center, Gansu Maternal and Child Health Care Hospital, Lanzhou, Gansu, China.Senior Nurse, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.Senior Technician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.Senior Technician, Center for Experimental Medicine, Lanzhou General Hospital, Lanzhou Military Command, Lanzhou, Gansu, China.Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver involvement, along with profound thrombocytopenia and mild to severe Acute Kidney Injury (AKI). These cases highlight the need for considering hantavirus testing in cases of thrombocytopenia, extreme leukocytosis, and fever of unknown origin, especially in areas endemic for the infection. https://jcdr.net/articles/PDF/10987/29306-CE(RA1)_F(GG)_PF1(PB_AP)_PFA(MJ_GG)_PF2(EK_MJ_AP).pdfacute kidney injuryliver involvementthrombocytopenia
collection DOAJ
language English
format Article
sources DOAJ
author Xiaopeng Yang
Sanming Chai
Xining Xu
Ling Hui
Meiliang Wang
spellingShingle Xiaopeng Yang
Sanming Chai
Xining Xu
Ling Hui
Meiliang Wang
Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
Journal of Clinical and Diagnostic Research
acute kidney injury
liver involvement
thrombocytopenia
author_facet Xiaopeng Yang
Sanming Chai
Xining Xu
Ling Hui
Meiliang Wang
author_sort Xiaopeng Yang
title Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
title_short Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
title_full Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
title_fullStr Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
title_full_unstemmed Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome
title_sort leukemoid reaction in complicated haemorrhagic fever with renal syndrome
publisher JCDR Research and Publications Private Limited
series Journal of Clinical and Diagnostic Research
issn 2249-782X
0973-709X
publishDate 2017-12-01
description Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver involvement, along with profound thrombocytopenia and mild to severe Acute Kidney Injury (AKI). These cases highlight the need for considering hantavirus testing in cases of thrombocytopenia, extreme leukocytosis, and fever of unknown origin, especially in areas endemic for the infection.
topic acute kidney injury
liver involvement
thrombocytopenia
url https://jcdr.net/articles/PDF/10987/29306-CE(RA1)_F(GG)_PF1(PB_AP)_PFA(MJ_GG)_PF2(EK_MJ_AP).pdf
work_keys_str_mv AT xiaopengyang leukemoidreactionincomplicatedhaemorrhagicfeverwithrenalsyndrome
AT sanmingchai leukemoidreactionincomplicatedhaemorrhagicfeverwithrenalsyndrome
AT xiningxu leukemoidreactionincomplicatedhaemorrhagicfeverwithrenalsyndrome
AT linghui leukemoidreactionincomplicatedhaemorrhagicfeverwithrenalsyndrome
AT meiliangwang leukemoidreactionincomplicatedhaemorrhagicfeverwithrenalsyndrome
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