Leukemoid Reaction in Complicated Haemorrhagic Fever with Renal Syndrome

Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver...

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Bibliographic Details
Main Authors: Xiaopeng Yang, Sanming Chai, Xining Xu, Ling Hui, Meiliang Wang
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-12-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/10987/29306-CE(RA1)_F(GG)_PF1(PB_AP)_PFA(MJ_GG)_PF2(EK_MJ_AP).pdf
Description
Summary:Hantaan Virus (HTNV) infections are mostly associated with fever, haemorrhagic and renal manifestations, known as Haemorrhagic Fever with Renal Syndrome (HFRS). We herein describe three cases with acute HTNV infection, confirming that HTNV infection may cause leukemoid reaction and prominent liver involvement, along with profound thrombocytopenia and mild to severe Acute Kidney Injury (AKI). These cases highlight the need for considering hantavirus testing in cases of thrombocytopenia, extreme leukocytosis, and fever of unknown origin, especially in areas endemic for the infection.
ISSN:2249-782X
0973-709X