The influence of glutathion S-transferase P-1 polymorphism A313G rs1695 on the susceptibility to cyclophosphamide hematologic toxicity in Indonesian patients

The influence of glutathion S-transferase P-1 polymorphism A313G rs1695 on the susceptibility to cyclophosphamide hematologic toxicity in Indonesian patients

Background: Chemotherapy often causes side effects such as hematologic toxicity. The degree of toxicity is often associated with genetic polymorphism. This study aims to determine the influence of GSTP1 A313G polymorphism, an enzyme responsible for detoxifying cyclophosphamid, on incidence and seve...

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Bibliographic Details
Main Authors: Dita Hasni, Kamal B. Siregar, Hadyanto Lim
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2016-07-01
Series:Medical Journal of Indonesia
Subjects:
breast cancer
cyclophosphamide
GSTP1 polymorphism
hematology toxicity
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/1308

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