Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis.
Infection with the white spot syndrome virus (WSSV) induces a metabolic shift in shrimp that resembles the "Warburg effect" in mammalian cells. This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways...
Main Authors: | Chun-Yuan Li, Yi-Jan Wang, Shiao-Wei Huang, Cheng-Shun Cheng, Han-Ching Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4709008?pdf=render |
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