Replication of the Shrimp Virus WSSV Depends on Glutamate-Driven Anaplerosis.

Infection with the white spot syndrome virus (WSSV) induces a metabolic shift in shrimp that resembles the "Warburg effect" in mammalian cells. This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways...

Full description

Bibliographic Details
Main Authors: Chun-Yuan Li, Yi-Jan Wang, Shiao-Wei Huang, Cheng-Shun Cheng, Han-Ching Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709008?pdf=render