Synthesis and anti-leukemic activity of pyrrolidinedione-thiazolidinone hybrids

Synthesis and anti-leukemic activity of pyrrolidinedione-thiazolidinone hybrids

A series of novel 2-(5-ylidene-4-oxo-2-thioxo-thiazolidin-3-yl)-succinimides and 5-ylidene-3-(1-arylpyrrolidine-2,5-dione)-thiazolidine-2,4-diones were synthesized. An efficient simple protocol for rhodanine-pyrrolidinedione hybrids synthesis which allows avoiding the step of anhydride formation was...

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Bibliographic Details
Main Authors:	A. Kryshchyshyn, D. Kaminskyy, O. Roman, R. Kralovics, O. Karpenko, R. Lesyk
Format:	Article
Language:	English
Published:	National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2020-04-01
Series:	Ukrainian Biochemical Journal
Subjects:	4-thiazolidinone anti-leukemic activity anticancer activity pyrrolidinedione
Online Access:	http://ukrbiochemjournal.org/wp-content/uploads/2020/04/Kryshchyshyn_2_20.pdf

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