Complex genetic interactions of novel Suppressor of Hairless alleles deficient in co-repressor binding.

Throughout the animal kingdom, the Notch signalling pathway allows cells to acquire diversified cell fates. Notch signals are translated into activation of Notch target genes by CSL transcription factors. In the absence of Notch signals, CSL together with co-repressors functions as a transcriptional...

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Bibliographic Details
Main Authors: Anette Preiss, Anja C Nagel, Heiko Praxenthaler, Dieter Maier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5839567?pdf=render