Hyperoside attenuates dextran sulfate sodium-induced colitis in mice possibly via activation of the Nrf2 signalling pathway

Hyperoside attenuates dextran sulfate sodium-induced colitis in mice possibly via activation of the Nrf2 signalling pathway

Abstract Background Hyperoside (Hyp) is a flavonoid glycoside compound that has been demonstrated to have anti-inflammatory, anti-apoptotic and antioxidant effects. However, the impact of Hyp on inflammatory bowel disease (IBD) has not been previously explored. Thus, we evaluated the role of Hyp in...

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Bibliographic Details
Main Authors: Lei Yang, Lei Shen, Yue Li, Yanxia Li, Shijie Yu, Shanshan Wang
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Journal of Inflammation
Subjects:
Hyperoside
DSS-induced colitis
Colonic inflammation
Apoptosis
Nrf2
Online Access:http://link.springer.com/article/10.1186/s12950-017-0172-5

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