Human Milk Oligosaccharides Modulate the Risk for Preterm Birth in a Microbiome-Dependent and -Independent Manner

Human Milk Oligosaccharides Modulate the Risk for Preterm Birth in a Microbiome-Dependent and -Independent Manner

The causes for preterm birth (PTB) often remain elusive. We investigated whether circulating human milk oligosaccharides (HMOs) might be involved in modulating urinary and vaginal microbiome promoting or preventing PTB. We identified here HMOs and key microbial taxa associated with indicators of PTB...

Full description

Bibliographic Details
Main Authors: Manuela-Raluca Pausan, Vassiliki Kolovetsiou-Kreiner, Gesa Lucia Richter, Tobias Madl, Elisabeth Giselbrecht, Barbara Obermayer-Pietsch, Eva-Christine Weiss, Evelyn Jantscher-Krenn, Christine Moissl-Eichinger
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mSystems
Subjects:
pregnancy
preterm delivery
vaginal and urinary microbiome
human milk oligosaccharides
inflammation
secretor status
3′-sialyllactose
3′sl
metabolites
preterm birth
tocolysis
urinary microbiome
vaginal microbiome
Online Access:https://doi.org/10.1128/mSystems.00334-20

Similar Items

Similar Items