Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy

Interleukin-22 Inhibits Respiratory Syncytial Virus Production by Blocking Virus-Mediated Subversion of Cellular Autophagy

Summary: Respiratory syncytial virus (RSV) infection can cause severe bronchiolitis in infants requiring hospitalization, whereas the elderly and immunocompromised are prone to RSV-induced pneumonia. RSV primarily infects lung epithelial cells. Given that no vaccine against RSV is currently availabl...

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Bibliographic Details
Main Authors: Sudipta Das, Claudette St. Croix, Misty Good, Jie Chen, Jinming Zhao, Sanmei Hu, Mark Ross, Michael M. Myerburg, Joseph M. Pilewski, John Williams, Sally E. Wenzel, Jay K. Kolls, Anuradha Ray, Prabir Ray
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Immunology
Virology
Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304429

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