Protein O-GlcNAcylation Promotes Trophoblast Differentiation at Implantation

Protein O-GlcNAcylation Promotes Trophoblast Differentiation at Implantation

Embryo implantation begins with blastocyst trophectoderm (TE) attachment to the endometrial epithelium, followed by the breaching of this barrier by TE-derived trophoblast. Dynamic protein modification with O-linked β-N-acetylglucosamine (O-GlcNAcylation) is mediated by O-GlcNAc transferase and O-Gl...

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Bibliographic Details
Main Authors: Peter T. Ruane, Cheryl M. J. Tan, Daman J. Adlam, Susan J. Kimber, Daniel R. Brison, John D. Aplin, Melissa Westwood
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cells
Subjects:
embryo implantation
stress
transcription factors
implantation failure
trophoblast differentiation
protein O-GlcNAcylation
Online Access:https://www.mdpi.com/2073-4409/9/10/2246

Internet

https://www.mdpi.com/2073-4409/9/10/2246

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