Genetic structure of the population and resistance to infections

Genetic structure of the population and resistance to infections

Numerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agen...

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Main Author: Sorin BUZINSCHI
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2020-06-01
Series:Romanian Journal of Medical Practice
Subjects:
genetic variability
inflammatory response sensors
factors that provide resistance to infections
covid-19 immunity
Online Access:https://rjmp.com.ro/articles/2020.2/RJMP_2020_2_Art-08.pdf
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spelling doaj-408d91ad9f5b4d2688f546a6078fbe6a2021-09-02T22:03:22ZengAmaltea Medical Publishing HouseRomanian Journal of Medical Practice1842-82582069-61082020-06-0115216817310.37897/RJMP.2020.2.8Genetic structure of the population and resistance to infectionsSorin BUZINSCHI0Facultatea de Medicină, Universitatea „Transilvania“, Braşov, RomâniaNumerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agents being considered consequences of the evolutionary pressure induced by the co-evolution of germs and population. The study presents examples related to these statements, the most notorious being the mutation of CCR5 delta-32 against HIV infection. Based on the genetic data, explanations are proposed regarding the very different evolution of people in the face of SARS-CoV-2 infection and the chances of an occult immunization of the population.https://rjmp.com.ro/articles/2020.2/RJMP_2020_2_Art-08.pdfgenetic variabilityinflammatory response sensorsfactors that provide resistance to infectionscovid-19 immunity
collection DOAJ
language English
format Article
sources DOAJ
author Sorin BUZINSCHI
spellingShingle Sorin BUZINSCHI
Genetic structure of the population and resistance to infections
Romanian Journal of Medical Practice
genetic variability
inflammatory response sensors
factors that provide resistance to infections
covid-19 immunity
author_facet Sorin BUZINSCHI
author_sort Sorin BUZINSCHI
title Genetic structure of the population and resistance to infections
title_short Genetic structure of the population and resistance to infections
title_full Genetic structure of the population and resistance to infections
title_fullStr Genetic structure of the population and resistance to infections
title_full_unstemmed Genetic structure of the population and resistance to infections
title_sort genetic structure of the population and resistance to infections
publisher Amaltea Medical Publishing House
series Romanian Journal of Medical Practice
issn 1842-8258
2069-6108
publishDate 2020-06-01
description Numerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agents being considered consequences of the evolutionary pressure induced by the co-evolution of germs and population. The study presents examples related to these statements, the most notorious being the mutation of CCR5 delta-32 against HIV infection. Based on the genetic data, explanations are proposed regarding the very different evolution of people in the face of SARS-CoV-2 infection and the chances of an occult immunization of the population.
topic genetic variability
inflammatory response sensors
factors that provide resistance to infections
covid-19 immunity
url https://rjmp.com.ro/articles/2020.2/RJMP_2020_2_Art-08.pdf
work_keys_str_mv AT sorinbuzinschi geneticstructureofthepopulationandresistancetoinfections
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