Genetic structure of the population and resistance to infections
Numerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agen...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2020-06-01
|
| Series: | Romanian Journal of Medical Practice |
| Subjects: | |
| Online Access: | https://rjmp.com.ro/articles/2020.2/RJMP_2020_2_Art-08.pdf |
| Summary: | Numerous studies have shown that populations behave differently in the face of infections through contagion, evolution, severity and mortality. Both susceptibility and resistance to infections have a strong genetic conditioning. Genetic polymorphisms offer vulnerability/resistance to infectious agents being considered consequences of the evolutionary pressure induced by the co-evolution of germs and population.
The study presents examples related to these statements, the most notorious being the mutation of CCR5 delta-32 against HIV infection. Based on the genetic data, explanations are proposed regarding the very different evolution of people in the face of SARS-CoV-2 infection and the chances of an occult immunization of the population. |
|---|---|
| ISSN: | 1842-8258 2069-6108 |