Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy

Increased plasma lipid levels exacerbate muscle pathology in the mdx mouse model of Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin expression and leads to severe ambulatory and cardiac function decline. However, the dystrophin-deficient mdx murine model of DMD only develops a very mild form of the disease. Our group and others have shown vascu...

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Bibliographic Details
Main Authors: Nadia Milad, Zoe White, Arash Y. Tehrani, Stephanie Sellers, Fabio M.V. Rossi, Pascal Bernatchez
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Skeletal Muscle
Subjects:
Duchenne muscular dystrophy
Vascular disease
Lipids
Dystrophin
Apolipoprotein E
Atherosclerosis
Online Access:http://link.springer.com/article/10.1186/s13395-017-0135-9

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