New lives given by cell death: Macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation

Monocytes that migrate into tissues during inflammatory episodes and differentiate to macrophages were classified earlier as simply two broad phenotypes: classically (M1)- or alternatively (M2)-activated macrophages, based on their exposure to different fate-determining mediators. These macrophage s...

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Bibliographic Details
Main Authors: Amiram eAriel, Charles Nicholas Serhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00004/full