Inhibition of NF-κB Signaling Reduces the Stemness Characteristics of Lung Cancer Stem Cells

Inhibition of NF-κB Signaling Reduces the Stemness Characteristics of Lung Cancer Stem Cells

Cancer stem cells (CSCs) are a subpopulation of cancer cells that play a pivotal role in tumor development, invasion, metastasis, and recurrence. We and others have reported significant involvement of the NF-κB pathway in regulating CSCs of non-small cell lung cancer (NSCLC). In this study, we evalu...

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Bibliographic Details
Main Authors: Norashikin Zakaria, Narazah Mohd Yusoff, Zubaidah Zakaria, Darius Widera, Badrul Hisham Yahaya
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Oncology
Subjects:
NF-κB signaling
lung cancer
cancer stem cells
cancer migration
self-renewal
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2018.00166/full

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