Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment

Cancer cells adapt their metabolism during tumorigenesis. We studied two isogenic breast cancer cells lines (highly metastatic 4T1; nonmetastatic 67NR) to identify differences in their glucose and glutamine metabolism in response to metabolic and environmental stress. Dynamic magnetic resonance spec...

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Bibliographic Details
Main Authors: Rui V. Simões, Inna S. Serganova, Natalia Kruchevsky, Avigdor Leftin, Alexander A. Shestov, Howard T. Thaler, George Sukenick, Jason W. Locasale, Ronald G. Blasberg, Jason A. Koutcher, Ellen Ackerstaff
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558615001013