Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report

Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report

Hailey-Hailey disease is an autosomal dominant genodermatosis leading to chronic hyperkeratotic and fissured lesions in the intertriginous areas. We present a 53-year-old woman with a case of vulvar and inguinal Hailey-Hailey disease resistant to usual treatments. She was efficiently treated with al...

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Main Authors: Alexandre Lemieux, Deana Funaro
Format: Article
Language:English
Published: SAGE Publishing 2020-02-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X20905678
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spelling doaj-406f65997640410eb6b2c2cdb08de4192020-11-25T03:20:02ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2020-02-01810.1177/2050313X20905678Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case reportAlexandre LemieuxDeana FunaroHailey-Hailey disease is an autosomal dominant genodermatosis leading to chronic hyperkeratotic and fissured lesions in the intertriginous areas. We present a 53-year-old woman with a case of vulvar and inguinal Hailey-Hailey disease resistant to usual treatments. She was efficiently treated with alitretinoin 10 mg daily combined with injections of onabotulinumtoxinA every 9 months. The combination led to an almost complete resolution of the lesions and symptoms at follow-ups.https://doi.org/10.1177/2050313X20905678
collection DOAJ
language English
format Article
sources DOAJ
author Alexandre Lemieux
Deana Funaro
spellingShingle Alexandre Lemieux
Deana Funaro
Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
SAGE Open Medical Case Reports
author_facet Alexandre Lemieux
Deana Funaro
author_sort Alexandre Lemieux
title Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
title_short Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
title_full Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
title_fullStr Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
title_full_unstemmed Recalcitrant vulvar Hailey-Hailey disease treated with alitretinoin and onabotulinumtoxinA: A case report
title_sort recalcitrant vulvar hailey-hailey disease treated with alitretinoin and onabotulinumtoxina: a case report
publisher SAGE Publishing
series SAGE Open Medical Case Reports
issn 2050-313X
publishDate 2020-02-01
description Hailey-Hailey disease is an autosomal dominant genodermatosis leading to chronic hyperkeratotic and fissured lesions in the intertriginous areas. We present a 53-year-old woman with a case of vulvar and inguinal Hailey-Hailey disease resistant to usual treatments. She was efficiently treated with alitretinoin 10 mg daily combined with injections of onabotulinumtoxinA every 9 months. The combination led to an almost complete resolution of the lesions and symptoms at follow-ups.
url https://doi.org/10.1177/2050313X20905678
work_keys_str_mv AT alexandrelemieux recalcitrantvulvarhaileyhaileydiseasetreatedwithalitretinoinandonabotulinumtoxinaacasereport
AT deanafunaro recalcitrantvulvarhaileyhaileydiseasetreatedwithalitretinoinandonabotulinumtoxinaacasereport
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