High mammographic density in women is associated with protumor inflammation

High mammographic density in women is associated with protumor inflammation

Abstract Background Epidemiological studies have consistently shown that increased mammographic density (MD) is a strong risk factor for breast cancer. We previously observed an elevated number of vimentin+/CD45+ leukocytes in high MD (HMD) epithelium. In the present study, we aimed to investigate t...

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Bibliographic Details
Main Authors: Cecilia W. Huo, Prue Hill, Grace Chew, Paul J. Neeson, Heloise Halse, Elizabeth D. Williams, Michael A. Henderson, Erik W. Thompson, Kara L. Britt
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Breast Cancer Research
Subjects:
Mammographic density
Immune infiltration
Macrophages
Dendritic cells
PD-L1
B cells
Online Access:http://link.springer.com/article/10.1186/s13058-018-1010-2

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