AMD-associated genes encoding stress-activated MAPK pathway constituents are identified by interval-based enrichment analysis.

AMD-associated genes encoding stress-activated MAPK pathway constituents are identified by interval-based enrichment analysis.

PURPOSE: To determine whether common DNA sequence variants within groups of genes encoding elements of stress-activated mitogen-activated protein kinase (MAPK) signaling pathways are, in aggregate, associated with advanced AMD (AAMD). METHODS: We used meta-regression and exact testing methods to ide...

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Bibliographic Details
Main Authors: John Paul SanGiovanni, Phil H Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734129?pdf=render

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