Automatic construction of metabolic models with enzyme constraints
Abstract Background In order to improve the accuracy of constraint-based metabolic models, several approaches have been developed which intend to integrate additional biological information. Two of these methods, MOMENT and GECKO, incorporate enzymatic (kcat) parameters and enzyme mass constraints t...
Main Authors: | Pavlos Stephanos Bekiaris, Steffen Klamt |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-019-3329-9 |
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