Impact of Host, Lifestyle and Environmental Factors in the Pathogenesis of MPN
Philadelphia-negative myeloproliferative neoplasms (MPNs) occur when there is over-production of myeloid cells stemming from hematopoietic stem cells with constitutive activation of JAK/STAT signaling, with <i>JAK2<sup>V617F</sup></i> being the most commonly occurring somatic...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-07-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/12/8/2038 |