In Vivo Thermodynamic Analysis of Glycolysis in Clostridium thermocellum and Thermoanaerobacterium saccharolyticum Using 13C and 2H Tracers

Thermodynamics constitutes a key determinant of flux and enzyme efficiency in metabolic networks. Here, we provide new insights into the divergent thermodynamics of the glycolytic pathways of C. thermocellum and T. saccharolyticum, two industrially relevant thermophilic bacteria whose metabolism sti...

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Bibliographic Details
Main Authors: Tyler B. Jacobson, Travis K. Korosh, David M. Stevenson, Charles Foster, Costas Maranas, Daniel G. Olson, Lee R. Lynd, Daniel Amador-Noguez
Format: Article
Language:English
Published: American Society for Microbiology 2020-03-01
Series:mSystems
Subjects:
mfa
Online Access:https://doi.org/10.1128/mSystems.00736-19