CD4+CD25+ regulatory T cell depletion modulates anxiety and depression-like behaviors in mice.

CD4+CD25+ regulatory T cell depletion modulates anxiety and depression-like behaviors in mice.

Stress has been shown to suppress immune function and increase susceptibility to inflammatory disease and psychiatric disease. CD4(+)CD25(+) regulatory T (Treg) cells are prominent in immune regulation. This study was conducted to determine if anti-CD25 antibody (Ab) mediated depletion of Treg cells...

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Bibliographic Details
Main Authors:	Soo-Jeong Kim, Hyojung Lee, Gihyun Lee, Sei-Joong Oh, Min-Kyu Shin, Insop Shim, Hyunsu Bae
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3409145?pdf=render

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