Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy
Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.
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Nature Publishing Group
2016-10-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms13354 |
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doaj-405043e189914752b01da6da98777da82021-05-11T11:03:52ZengNature Publishing GroupNature Communications2041-17232016-10-017111010.1038/ncomms13354Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapyJu Yeon Lee0Hyun Tae Lee1Woori Shin2Jongseok Chae3Jaemo Choi4Sung Hyun Kim5Heejin Lim6Tae Won Heo7Kyeong Young Park8Yeon Ji Lee9Seong Eon Ryu10Ji Young Son11Jee Un Lee12Yong-Seok Heo13Department of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Bio Engineering, Hanyang UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityDepartment of Chemistry, Konkuk UniversityImmunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets.https://doi.org/10.1038/ncomms13354 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ju Yeon Lee Hyun Tae Lee Woori Shin Jongseok Chae Jaemo Choi Sung Hyun Kim Heejin Lim Tae Won Heo Kyeong Young Park Yeon Ji Lee Seong Eon Ryu Ji Young Son Jee Un Lee Yong-Seok Heo |
| spellingShingle |
Ju Yeon Lee Hyun Tae Lee Woori Shin Jongseok Chae Jaemo Choi Sung Hyun Kim Heejin Lim Tae Won Heo Kyeong Young Park Yeon Ji Lee Seong Eon Ryu Ji Young Son Jee Un Lee Yong-Seok Heo Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy Nature Communications |
| author_facet |
Ju Yeon Lee Hyun Tae Lee Woori Shin Jongseok Chae Jaemo Choi Sung Hyun Kim Heejin Lim Tae Won Heo Kyeong Young Park Yeon Ji Lee Seong Eon Ryu Ji Young Son Jee Un Lee Yong-Seok Heo |
| author_sort |
Ju Yeon Lee |
| title |
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| title_short |
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| title_full |
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| title_fullStr |
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| title_full_unstemmed |
Structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| title_sort |
structural basis of checkpoint blockade by monoclonal antibodies in cancer immunotherapy |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2016-10-01 |
| description |
Immunotherapy is offering patients with cancer new therapy options. Here, the authors report on the crystal structures of some of these therapies bound to their targets. |
| url |
https://doi.org/10.1038/ncomms13354 |
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1721447105510244352 |