Number of T- and B-lymphocytes and their functional activity in the blood of common carps aff ected by Aeromonosis, and in the treatment of probiotic Enteronormin

• Main Authors: Solopova Kh., Vishchur O.
• Format: Article
• Language: English
• Published: Bila Tserkva National Agrarian University 2020-05-01
• Series: Науковий вісник ветеринарної медицини
• Subjects: fi sh; carp; aeromonosis; probiotics; enteronormin; t-lymphocytes; b-lymphocytes
• Online Access: http://nvvm.btsau.edu.ua/sites/all/modules/pubdlcnt/pubdlcnt.php?fid=1004
• ISSN: 2310-4902; 2415-7589

Fish bacterial infectious diseases are a signifi cant problem for aquaculture, often leading to massive fi sh deaths and signifi cant economic losses. For fi sh treatment often used antibacterial drugs: nitrofuran, antibiotics, feed antibiotics, as well as dyes. Finding eff ective drugs and studying their eff ects on the body of fi sh are relevant. Nowadays, diff erent groups of substances, including probiotics, are off ered as an alternative to increase the growth of animals and to combat pathogens. Here are the results of studies of the infl uence of the probiotic drug "Enteronormin" on the indicators that characterize the status of T- and B-cell immunity of carp aff ected by bacterial Aeromonosis. Enteronormin is a probiotic supplement , wich contains a bacteria complex - Enterococcus spp, Bacillus subtilis spp, Lactobacillus spp; and excipients - chitosan, peptone enzymatic and ground sugar (РП № ВВ-00427-02-12 від 13.04.2012). The research was conducted under the conditions of aquariums at the Lviv Research Station of the Institute of Fisheries of NAAS. The control group, which consisted of clinically healthy fi sh, received only 3% starch suspension, the fi rst experimental group (D1) - Aeromonosis aff ected carps who were given only 3% starch suspension, the second experimental group (D2), which consisted of carps aff ected Aeromonosis, through the probe within 7 days was administered the drug "Enteronormin", at the rate of 2 mg per 1 kg of fi sh weight, in the composition of 3% starch suspension. Before feeding for the carp drug was activated for 14-16 hours water enriched with Iodine and Selenium ions in the Jodis + Se form (TU U 15.7-30631018-011: 2011). It is established that the disease of carp on Aeromonosis leads to changes in the number and functional activity of immunocompetent blood cells. The inhibition of lymphocytogenesis and functional activity of immunocompetent cells in carp blood in a disease associated with the bacterial form of aeromonosis was ascertained. The use in the experimental carps group in the composition of 3% starch suspension of the drug "Enteronormin" had a normalizing eff ect on the state of T-cell specifi c protection, but did not signifi cantly aff ect the amount of EAC-RUL and their functional activity.