FAMILIAL ALOPECIA ARETA, ATOPY AND THYROIDITIS HASHIMOTO

• Main Authors: Ani Tsvetanova, Dimitar Gospodinov, Mariana Trashlieva
• Format: Article
• Language: English
• Published: Peytchinski Publishing 2004-10-01
• Series: Journal of IMAB
• Subjects: familial alopecia areata; thyreoiditis Hashimoto; "Atopic type" of alopecia areata; Ikeda´s classification; morbid associations of alopecia areata
• Online Access: http://www.journal-imab-bg.org/statii/32-35_b1-04.pdf

We present a case of morbid association of two organ-specific autoimmune diseases (Alopecia areata-AA and Thyreoiditis Hashimoto-TH) in two white sisters - 23 and 26 years old. There is no family history of AA or any autoimmune disorders. The onset of AA, in the both sisters was in early childhood (3 and 7 years of age). The clinical and laboratory examinations showed engagement of the scalp with round or oval large patches of alopecia, without involvement of the body hairs and nails. There were also alterations of thyroid gland function, positive TMA (Thyroid Microsomal Antibodies) and Rö-data of Pituitary adenoma as well as episodes of allergic rhinitis (in one of the sisters), and bronchial asthma (in the other). According to Ikeda’s classification, they have an "Atopic type" AA. We suppose that the observed case is not an occasional coincidence of AA and TH. HLA Aw32B18 determination could be support our suggesting about the familial pattern of these autoimmune diseases.